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2022

Copyright (c) 2022 Jhon Henry Osorio Castaño, Yurani Marcela Jaramillo Córdoba

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This work is licensed under a Creative Commons Attribution 4.0 International License.

High-grade intraepithelial lesion and its relationship with intracervical neoplasm and cervical cancer

https://doi.org/10.17081/innosa.159
Jhon Henry Osorio Castaño
Universidad Pontificia Bolivariana
Yurani Marcela Jaramillo Córdoba
Clínica San Juan de Dios, Colombia

Corresponding Author(s) : Jhon Henry Osorio Castaño

jhon.osorio@upb.edu.co

Ciencia e Innovación en Salud, 2022

Abstract

Introduction: the purpose of the study was to identify the social and clinical characteristics of women with high-grade intraepithelial lesions and their relationship with intracervical neoplasms and cervical cancer. Methods: observational study with analytical intention where all women with the modification described in the period 2013-2019 were included. Qualitative and quantitative variables were analyzed and a bivariate analysis was performed with calculation of OR to identify associations. Results: 29.8% belonged to the group between 30 and 39 years old, 36.6% agreed to the colposcopy in the first thirty days, 5.4% had a diagnosis of cancer and 31.4% of neoplasm of High grade, the subsidized regimen, and major or cancer-suggestive changes on colposcopy were associated with cancer or grade II/III neoplasms. Conclusion: high-grade intraepithelial lesion is considered an alteration of the risk for the appearance of cervical cancer and intracervical neoplasia.

Keywords

cytology, squamous intraepithelial lesions of the cervix, uterine cervical neoplasms, colposcopy, papillomavirus infections
1.
Osorio Castaño JH, Jaramillo Córdoba YM. High-grade intraepithelial lesion and its relationship with intracervical neoplasm and cervical cancer. Ciencia e Innovación en Salud [Internet]. 2022 Oct. 26 [cited 2024 Nov. 13];. Available from: https://revistas.unisimon.edu.co/index.php/innovacionsalud/article/view/5650
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References
  • Agency I for R on cancer. Cancer today [Internet]. 2020 [cited 2020 Nov 15]. Available from: https://gco.iarc.fr/
  • Salud OP de la. Cáncer de cérvix [Internet]. 2019 [cited 2020 Nov 15]. Available from: https://www.paho.org/es
  • Cáncer ON de. Indicadores [Internet]. 2020. [cited 2020 Nov 15]. Available from: https://www.sispro.gov.co/observatorios/oncancer/indicadores/Paginas/Indicadores.aspx
  • Puerto M, Moreno P, Mora M, Pérez C. Citología convencional y e base liquida en muestra compartida de tomas cervicouterinas. Repert.med.cir. 2015;24(1):41–6.
  • Moreno M. Actualización en el reporte de citología cervicovaginal basado en el Sistema Bethesda 2014. Rev Obs Ginecol Venez [Internet]. 2017;77(1):58–66. Available from: http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S0048-77322017000100008
  • Yela W, Valencia M. Comportamiento de las alteraciones citológicas y algunos factores asociados en mujeres atendidas en una IPS Pública del Suroeste Antioqueño, julio-2014 a julio-2015. Hechos Microbiol. 2015;6(1–2):12–20.
  • Osorio-Castaño J., Pérez-Villa M, Montoya-Zapata C., Cardona-Restrepo F. Características citológicas previas al diagnóstico de cáncer de cérvix en mujeres de Medellín (Colombia). Univ y Salud. 2020;22(3):231–7.
  • Gupta R, Sodhani P, Mehrotra R, Gupta S. Cervical high-grade squamous intraepithelial lesion on conventional cytology: Cytological patterns, pitfalls, and diagnostic clues. Diagn Cytopathol. 2019;47(12):1267–76.
  • Zapata M, Sánchez M. Prevalencia de lesiones intraepiteliale escamosas y cáncer de cuello uterino en mujeres del Oriente Antioqueño, Colombia 2019. Universidad de Antioquia; 2020.
  • Cordeiro J, Goncalvez A, Guerreiro I, Junior J, da Silva T, Bruneska D, et al. High risk HPV E6/E7 oncoprotein expression in women with high grade squamous intraepithelial lesion. Rev Bras Ginecol e Obstet. 2016;38(3):154–9.
  • Xavier-Junior J, Mucha R, Bhadra D, Tavares M, Zeferino L. Early age at first sexual intercourse is associated with higher prevalence of high-grade squamous intraepithelial lesions (HSIL). Revi Bras Ginecol Obs. 2017;39(2):80–5.
  • De Sousa K, Colmenares E. Prevalencia de lesiones intraepiteliales cervicales de bajo y alto grado en pacientes en edad fértil. Maracaibo. Estado Zulia. Rev Digit Postgrado. 2019;8(3):e179.
  • Solís J, Briones-Torres T. Prevalencia de lesión intraepitelial en citología cervical de tamizaje en una unidad de primer nivel de atención. Rev Med Inst Mex Seguro Soc [Internet]. 2018;56(2):167–72. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29902371
  • Gu L, Hong Z, Gao H, Qiu L, Di W. Incidence of cervical high-grade squamous intraepithelial lesions and squamous cell carcinoma in women with high-risk human papillomavirus and normal cervical cytology: A retrospective analysis of 1858 cases stratified by age and human papillomavirus genotype. Cytopathology. 2019;30(4):419–25.
  • Sun H, Masand R, Patel S, Padmanabhan V. High grade squamous intraepithelial lesion on high-risk HPV negative patients: Why we still need the Pap test. Diagn Cytopathol. 2018;46(11):908–13.
  • Abolafia-Cañete B, Monserrat-Jordán J, Cuevas-Cruces J, Arjona Berral J. Diagnóstico precoz del cáncer de cérvix: Correlación entre citología, colposcopia y biopsia. Rev Española Patol. 2018;51(3):147–53.
  • Ciendua G, Ortiz N, Alvarado C, Balaguera AV, Colmenares CC. Hallazgos en colposcopia. Experiencia en una unidad de referencia. Ginecol Obstet Mex. 2019;87(5):302–10.
  • García-López T, León-Hernández J, García-Perdomo H, Pacheco R. Evaluación de un programa de detección temprana de cáncer cervicouterino en Colombia. Rev Colomb Cancerol [Internet]. 2017;21(3):143–51. Available from: http://dx.doi.org/10.1016/j.rccan.2017.09.001
  • Calderón D. Diagnóstico y tratamiento de las lesiones intraepiteliales escamosas de alto grado del cuello uterino. Cambios rev med. 2019;18(1):76–84.
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