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Copyright (c) 2019 Ivan David Lozada Martinez, Maria Bolaño Romero, Luis Herrera Zabaleta, Sandra Herrera Lomonaco , Francisco Herrera Sáenz
This work is licensed under a Creative Commons Attribution 4.0 International License.
Papillary breast carcinoma in men: a rare presentation
Corresponding Author(s) : Ivan David Lozada Martinez
Ciencia e Innovación en Salud,
2019
Abstract
Introduction: The male breast encompasses a number of conditions that can be both benign and malignant, the most common cause of increased male breast, gynecomastia. Male breast cancer is a very rare entity that accounts for less than 1% of all breast cancers.
Case Report: We present the case of a 44-year-old patient, who is presented to the emergency department by a picture of approximately one year of evolution, consisting of tumefaction located in left breast with erythema and pain, becoming the diagnosis of mass tumor.
Discussion: Male breast cancer is an uncommon entity, accounting for about 1% of all male cancers. The most commonly observed histological subtypes of male breast cancer are non-special invasive carcinoma (84-90%) papillary carcinoma (2-5%). The other histological subtypes are very rare.
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- Shaaban AM. Pathology of the male breast. Diagnostic Histopathology. 2019; 24: 138-42. https://www.diagnostichistopathology.co.uk/article/S1756-2317(19)30005-2/abstract
- Sun HF, Zhao Y, Gao SP, Li LD, Fu WY, Jiang HL, Chen MT, Yang LP, Jin W. Clinicopathological characteristics and survival outcomes of male breast cancer according to race: a SEER population-based study. Oncotarget. 2017; 8: 69680-90. https://www.ncbi.nlm.nih.gov/pubmed/29050233
- Gómez RC, Zambrana F, Serreno M, López M, Casado E. Male breast cancer. Cancer Treatment Reviews. 2010; 36:451-7. https://www.ncbi.nlm.nih.gov/pubmed/20193984
- Mesa G, Matute G, Estrada M, Ocampo A, Restrepo C, Estrada J. Cáncer mamario en hombres. Rev Colomb Cir. 2011; 26:293-307. http://www.scielo.org.co/pdf/rcci/v26n4/v26n4a7.pdf
- Trépant AL, Hoorens A, Noël JC. Pure invasive micropapillary carcinoma of the male breast: report of a rare case with C-MYC amplification. Pathol Res Pract. 2014; 210(12):1164-6. https://www.ncbi.nlm.nih.gov/pubmed/25042382
- Lakhani SR, WHO Classification of Tumours of the Breast. Fourth ed., International Agency for research on cancer, Lyon. 2012; 65:168. http://apps.who.int/bookorders/anglais/detart1.jsp?codlan=1&codcol=70&codcch=4004
- American Cancer Society. What are the key statistics about breast cancer in men? Atlanta. [Internet]. [Consultado 9 Sep 2019]. Disponible en: https://www.cancer.org/cancer/breast-cancer-in-men/about/key-statistics.html
- Anand G, Al-Khalisi N, Arif D, Hamidpour S, Lewis T. Rare case of male breast intraductal papilloma progressing to invasive ductal carcinoma: A radiologic-pathologic correlation. Radiol Case Rep. 2018; 13(3):602-605. https://www.ncbi.nlm.nih.gov/pubmed/30073044
- Selcukbiricik F, Tural D, Aydoğan F, Beşe N, Büyükünal E, Serdengeçti S. Male breast cancer: 37-year data study at a single experience center in Turkey. J Breast Cancer. 2013; 16(1):60-5. https://www.ncbi.nlm.nih.gov/pubmed/23593083
- Jamy O, Rafiq A, Laghari A, Chawla T. Male breast cancer: a 24 year experience of a tertiary care hospital in Pakistan. Asian Pac J Cancer Prev. 2015; 16(4):1559-63. https://www.ncbi.nlm.nih.gov/pubmed/25743831
- Amirifard N, Sadeghi E, Payandeh M, Mohebbi H, Sadeghi M, Choubsaz M. Relationship between HER2 Proto-oncogene status and prognostic factors of breast cancer in the west of Iran. Asian Pac J Cancer Prev. 2016; 17:295-8. https://www.ncbi.nlm.nih.gov/pubmed/26838227
- Amirifard N, Sadeghi E. Breast Cancer in Men: a Report from the Department of Radiation Oncology in Kermanshah Province, Iran. Asian Pac J Cancer Prev. 2016; 17(5): 2593-2596. https://europepmc.org/abstract/med/27268636
- Rodrigues FR, da Silva AV, de Oliveira Teixeira CM, Antunes SC, Rochael MC. Two cases of male breast cancer at a university hospital in southeast Brazil. Int J Gen Med. 2013; 6:503–506. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698024/
- Yılmaz R, Günöz Cömert R, Aliyev S, Toktaş Y, Önder S, Önder S, Emirikçi S, Özmen V. Encapsulated Papillary Carcinoma in A Man with Gynecomastia: Ultrasonography, Mammography and Magnetic Resonance Imaging Features with Pathologic Correlation. Eur J Breast Health. 2018; 14: 127-131. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939977/
- Rodríguez MC, Secades AL, Angulo JM. Best cases from the AFIP: intracystic papillary carcinoma of the breast. Radiographics. 2010; 30:2021- 2027. https://www.ncbi.nlm.nih.gov/pubmed/21057133
- Kumar H, Ail DA, Prakash G. Intracystic papillary carcinoma of the breast with associated invasive carcinoma: a rare case report. Res Rev J Med Heal Sci. 2014; 3:43–46. https://www.ncbi.nlm.nih.gov/pubmed/28764176
- Kishor HS, Dhiraj BN, Rajshri PD, Dravid N, Tayde Y. An Unusual case of intracystic papillary carcinoma of breast with invasive component. Int J Med Res Heal Sci. 2014;3:762-65. http://www.indianjournals.com/ijor.aspx?target=ijor:ijmrhs&volume=3&issue=3&article=049
- Rakha EA, Ellis IO. Diagnostic challenges in papillary lesions of the breast. Pathology. 2018; 50(1):100-110. https://www.ncbi.nlm.nih.gov/pubmed/29179906
- Kumar M, Pottipati B, Arakeri SU, Javalgi AP. Infiltrating Ductal Carcinoma Co-Existing with Intraductal Papillary Carcinoma of Male Breast: A Rare Case Report. J Clin Diagn Res. 2017; 11(6):ED04-ED05. https://www.ncbi.nlm.nih.gov/pubmed/28764176
- Javidiparsijani S, Rosen LE, Gattuso P. Male breast carcinoma: a clinical and pathological review. Int J Surg Pathol. 2017; 25(3):200–5. https://journals.sagepub.com/doi/abs/10.1177/1066896916675953
- Kinoshita H, Kashiwagi S, Teraoka H, Mori T, Kuroda K, Nanbara M, Noda E, Chikugo T, Hirakawa K, Ohira M. Intracystic papillary carcinoma of the male breast: a case report. World J Surg Oncol. 2018; 16(1):15). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781267/
References
Shaaban AM. Pathology of the male breast. Diagnostic Histopathology. 2019; 24: 138-42. https://www.diagnostichistopathology.co.uk/article/S1756-2317(19)30005-2/abstract
Sun HF, Zhao Y, Gao SP, Li LD, Fu WY, Jiang HL, Chen MT, Yang LP, Jin W. Clinicopathological characteristics and survival outcomes of male breast cancer according to race: a SEER population-based study. Oncotarget. 2017; 8: 69680-90. https://www.ncbi.nlm.nih.gov/pubmed/29050233
Gómez RC, Zambrana F, Serreno M, López M, Casado E. Male breast cancer. Cancer Treatment Reviews. 2010; 36:451-7. https://www.ncbi.nlm.nih.gov/pubmed/20193984
Mesa G, Matute G, Estrada M, Ocampo A, Restrepo C, Estrada J. Cáncer mamario en hombres. Rev Colomb Cir. 2011; 26:293-307. http://www.scielo.org.co/pdf/rcci/v26n4/v26n4a7.pdf
Trépant AL, Hoorens A, Noël JC. Pure invasive micropapillary carcinoma of the male breast: report of a rare case with C-MYC amplification. Pathol Res Pract. 2014; 210(12):1164-6. https://www.ncbi.nlm.nih.gov/pubmed/25042382
Lakhani SR, WHO Classification of Tumours of the Breast. Fourth ed., International Agency for research on cancer, Lyon. 2012; 65:168. http://apps.who.int/bookorders/anglais/detart1.jsp?codlan=1&codcol=70&codcch=4004
American Cancer Society. What are the key statistics about breast cancer in men? Atlanta. [Internet]. [Consultado 9 Sep 2019]. Disponible en: https://www.cancer.org/cancer/breast-cancer-in-men/about/key-statistics.html
Anand G, Al-Khalisi N, Arif D, Hamidpour S, Lewis T. Rare case of male breast intraductal papilloma progressing to invasive ductal carcinoma: A radiologic-pathologic correlation. Radiol Case Rep. 2018; 13(3):602-605. https://www.ncbi.nlm.nih.gov/pubmed/30073044
Selcukbiricik F, Tural D, Aydoğan F, Beşe N, Büyükünal E, Serdengeçti S. Male breast cancer: 37-year data study at a single experience center in Turkey. J Breast Cancer. 2013; 16(1):60-5. https://www.ncbi.nlm.nih.gov/pubmed/23593083
Jamy O, Rafiq A, Laghari A, Chawla T. Male breast cancer: a 24 year experience of a tertiary care hospital in Pakistan. Asian Pac J Cancer Prev. 2015; 16(4):1559-63. https://www.ncbi.nlm.nih.gov/pubmed/25743831
Amirifard N, Sadeghi E, Payandeh M, Mohebbi H, Sadeghi M, Choubsaz M. Relationship between HER2 Proto-oncogene status and prognostic factors of breast cancer in the west of Iran. Asian Pac J Cancer Prev. 2016; 17:295-8. https://www.ncbi.nlm.nih.gov/pubmed/26838227
Amirifard N, Sadeghi E. Breast Cancer in Men: a Report from the Department of Radiation Oncology in Kermanshah Province, Iran. Asian Pac J Cancer Prev. 2016; 17(5): 2593-2596. https://europepmc.org/abstract/med/27268636
Rodrigues FR, da Silva AV, de Oliveira Teixeira CM, Antunes SC, Rochael MC. Two cases of male breast cancer at a university hospital in southeast Brazil. Int J Gen Med. 2013; 6:503–506. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698024/
Yılmaz R, Günöz Cömert R, Aliyev S, Toktaş Y, Önder S, Önder S, Emirikçi S, Özmen V. Encapsulated Papillary Carcinoma in A Man with Gynecomastia: Ultrasonography, Mammography and Magnetic Resonance Imaging Features with Pathologic Correlation. Eur J Breast Health. 2018; 14: 127-131. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939977/
Rodríguez MC, Secades AL, Angulo JM. Best cases from the AFIP: intracystic papillary carcinoma of the breast. Radiographics. 2010; 30:2021- 2027. https://www.ncbi.nlm.nih.gov/pubmed/21057133
Kumar H, Ail DA, Prakash G. Intracystic papillary carcinoma of the breast with associated invasive carcinoma: a rare case report. Res Rev J Med Heal Sci. 2014; 3:43–46. https://www.ncbi.nlm.nih.gov/pubmed/28764176
Kishor HS, Dhiraj BN, Rajshri PD, Dravid N, Tayde Y. An Unusual case of intracystic papillary carcinoma of breast with invasive component. Int J Med Res Heal Sci. 2014;3:762-65. http://www.indianjournals.com/ijor.aspx?target=ijor:ijmrhs&volume=3&issue=3&article=049
Rakha EA, Ellis IO. Diagnostic challenges in papillary lesions of the breast. Pathology. 2018; 50(1):100-110. https://www.ncbi.nlm.nih.gov/pubmed/29179906
Kumar M, Pottipati B, Arakeri SU, Javalgi AP. Infiltrating Ductal Carcinoma Co-Existing with Intraductal Papillary Carcinoma of Male Breast: A Rare Case Report. J Clin Diagn Res. 2017; 11(6):ED04-ED05. https://www.ncbi.nlm.nih.gov/pubmed/28764176
Javidiparsijani S, Rosen LE, Gattuso P. Male breast carcinoma: a clinical and pathological review. Int J Surg Pathol. 2017; 25(3):200–5. https://journals.sagepub.com/doi/abs/10.1177/1066896916675953
Kinoshita H, Kashiwagi S, Teraoka H, Mori T, Kuroda K, Nanbara M, Noda E, Chikugo T, Hirakawa K, Ohira M. Intracystic papillary carcinoma of the male breast: a case report. World J Surg Oncol. 2018; 16(1):15). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781267/