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2022

Copyright (c) 2022 Christian German Ospina Pérez, Ivan David Lozada Martínez, José Carlos Posada Viana, Bernarda Cuadrado Cano

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Factors associated with pancreatitis after endoscopic retrograted cholangiopancreatography: a single center's experience in the Colombian Caribbean

https://doi.org/10.17081/innosa.147
Christian German Ospina Pérez
Universidad de Cartagena
Ivan David Lozada Martínez
Universidad de Cartagena
José Carlos Posada Viana
Universidad de Cartagena
Bernarda Cuadrado Cano
Universidad de Cartagena

Corresponding Author(s) : Ivan David Lozada Martínez

ivandavidloma@gmail.com

Ciencia e Innovación en Salud, 2022

Abstract

Background: Currently, endoscopic retrograde cholangiopancreatography (ERCP) is one of the most useful studies in the therapeutic approach to pancreato-biliary diseases. However, being an invasive procedure, it carries a certain risk of complications, such as pancreatitis. In Latin America, there is a great lack of epidemiological research on factors associated with the development of post-ERCP pancreatitis. Methods: Retrospective, quantitative and analytical case-control research, where patients older than 18 years who had undergone ERCP between 2013-2018 were included. Controls were chosen in a 2:1 ratio, evaluating sociodemographic, clinical, paraclinical, surgical and post-surgical variables. Results:  A total of 180 ERCPs were identified, 32 cases of post-ERCP pancreatitis were detected (17.8%), and 64 patients were taken as controls. In the sample, female sex, pre-surgical ASA grade I, and pre-surgical diagnosis of predominantly lithiasis prevailed. When assessing risk by crude OR, there was an association of post-ERCP pancreatitis with the presence of abdominal pain (OR 4.2; 95% CI 1.6-10.7), pancreatic pain (OR 3.2; 95% CI 2. 3-4.3), vomiting (OR 4.2; 95% CI 1.1-15.6), abdominal distension (OR 8.3, 95% CI 2.4-10.4), lipase > 948 IU/L (OR 8.3; 95% CI 2.4-10.4) and amylase greater than 350 IU/L (OR 1.4; 95% CI 5.0-20.4). Conclusions:   Factors associated with post-ERCP pancreatitis were abdominal pain, pancreatic pain, vomiting, abdominal distension, elevated lipase and amylase

Keywords

Pancreatitis, Endoscopic Retrograted Cholangiopancreatography, Endoscopy, Diagnostic Techniques and Procedures, Risk Factors
1.
Ospina Pérez CG, Lozada Martínez ID, Posada Viana JC, Cuadrado Cano B. Factors associated with pancreatitis after endoscopic retrograted cholangiopancreatography: a single center’s experience in the Colombian Caribbean. Ciencia e Innovación en Salud [Internet]. 2022 Mar. 16 [cited 2024 Nov. 13];. Available from: https://revistas.unisimon.edu.co/index.php/innovacionsalud/article/view/5271
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